Reference
Where these molecules were found
These desks found, tested, or standardised the five medicines on this folio. History explains the hold.
Kitasato Institute
5-9-1 Shirokane, Minato City, Tokyo 108-8641, Japan
The Tokyo laboratory where Satoshi Omura's soil-microbe screen produced the avermectin lead behind ivermectin.
Merck Sharp & Dohme (Rahway)
126 East Lincoln Avenue, Rahway, NJ 07065, USA
Where William Campbell's team turned avermectin into ivermectin and later launched the Mectizan donation programme.
Former Pfizer Discovery Laboratories
Ramsgate Road, Sandwich, Kent CT13 9NJ, United Kingdom
The Kent site where sildenafil was tested for angina and its erectile side effect was first taken seriously.
ICOS Corporation (historic)
22021 20th Avenue SE, Bothell, WA 98021, USA
The Washington biotech that discovered tadalafil before partnering with Eli Lilly to market Cialis.
Bayer AG Pharmaceuticals
Friedrich-Ebert-Strasse 217, 42117 Wuppertal, Germany
The German laboratories that developed vardenafil, later sold as Levitra and the orodispersible Staxyn.
Eli Lilly and Company
893 Delaware Street, Indianapolis, IN 46285, USA
Developer of fluoxetine - the SSRI, launched as Prozac, that reshaped how depression is treated.
U.S. Food and Drug Administration
10903 New Hampshire Avenue, Silver Spring, MD 20993, USA
The agency whose current prescribing information anchors every dose and warning quoted in this compendium.
World Health Organization
Avenue Appia 20, 1211 Geneva 27, Switzerland
Keeper of the Model List of Essential Medicines, which lists ivermectin and fluoxetine among core medicines.
Why the history sits on the folio
A soil screen in Tokyo explains why ivermectin is a parasite tablet, not a viral one. An angina miss in Sandwich explains why sildenafil carries a nitrate hold. A German selectivity file explains why vardenafil still asks about QT neighbours. Each slip points back at the desk that shaped it.